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Selected safety information,
including boxed warning on use
in pregnancy.
Merck
COZAAR® (losartan potassium tablets) & HYZAAR® (losartan potassium-hydrochlorothiazide tablets)

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USE IN PREGNANCY: When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, COZAAR and HYZAAR should be discontinued as soon as possible. See WARNINGS: Fetal/Neonatal Morbidity and Mortality.
This site is intended only for health care professionals of the United States, its territories, and Puerto Rico.
COZAAR and HYZAAR are registered trademarks of E.I. du Pont de Nemours and Company, Wilmington, Delaware, USA.
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